For 23 years she was homeported in Panama City, Florida. In January 1992, the ship and her crew relocated to Galveston, Texas. Portsmouth, Virginia was her home before being relocated to her new home in Cape May, New Jersey, on August 4, 2000. On May 30, 2015 her homeport was shifted to Joint Expeditionary Base Little Creek-Fort Story in Virginia Beach, Virginia. Her mission remains the same in Virginia Beach as in the past. Examples of her missions include enforcing fishery regulations in the Atlantic, interdicting drug traffickers in the Caribbean, and rescuing Cuban and Haitian migrants in the Florida Straits.
In her 3rd year conducting law enforcement patrols, the crew intercepted and interdicted 15% of the marijuana seized by the entire Coast Guard. The highlight of 1978 was in August when she seized the merchant vessel “Heide”, which was carrying over 240,000 lb (110,000 kg). of marijuana. She then went on to receive national recognition on August 23, 1981 when seizing the fishing vessel “Sea King” for trafficking 9 tons of marijuana. In February 2000, she participated in a joint effort with a Coast Guard Law Enforcement Detachment. After the detachment seized fishing vessel “Rebelde”, she towed the vessel from Cristobal, Panama and transported 6 tons of cocaine and 7 smugglers to Tampa, Florida, for prosecution. The journey lasted several days and covered 1,250 nautical miles (2,320 km).
The Dependable has received several awards including three Coast Guard Unit Commendations. She also has received two Coast Guard Meritorious Unit Commendations and the Humanitarian Service Medal for her lifesaving operations during the 1980 Cuban exodus.